PharmaVentures advises Novartis on the sale of its manufacturing facility in Barberà del Vallès to Siegfried Holding AG

Divestment of a Pharmaceutical Manufacturing Facility in Barberà del Vallès, Spain

PharmaVentures advises Novartis on the sale of its manufacturing facility in Barberà del Vallès to Siegfried Holding AG.

Oxford, UK, 5th October 2020

PharmaVentures Ltd (“PharmaVentures”) is pleased to announce that it was the corporate finance advisor to Novartis on the divestment of its manufacturing facility in Barberà del Vallès, Spain, to Siegfried Holding AG, a global contract development and manufacturing organisation (CDMO).

PharmaVentures is a premier transaction advisory firm; a world leader in partnering, pharma M&A deals and strategic alliances.

An unrivalled bank of specialist experience, deal analytics and network of contacts among innovators and large pharma makes PharmaVentures uniquely placed to support healthcare businesses in all aspects of deal-making and strategic planning. PharmaVentures is well known for its deep insight into deal structures and its success for generating partnering interest.

PharmaVentures Capital Ltd is a wholly owned subsidiary of PharmaVentures Ltd. All regulated activities are delivered through PharmaVentures Capital Ltd, which is authorised and regulated by the Financial Conduct Authority (741356). PharmaVentures Capital Ltd undertakes regulated activities for and on behalf of professional clients only as defined in the FCA handbook COBS 3.5.

For press enquiries, please contact:

Lisa Holloway

Senior Marketing Manager

PharmaVentures Ltd

enquiries@pharmaventures.com

+44 (0) 1865 332700

PharmaVentures advises Vital Foods on the sale of its Zyactinase-based digestive health product asset portfolio to Mundipharma

Sale of Zyactinase assets to Mundipharma

PharmaVentures advises Vital Foods on the sale of its Zyactinase-based digestive health product asset portfolio to Mundipharma.

For press enquiries, please contact:

Lisa Holloway

Senior Marketing Manager

PharmaVentures Ltd

enquiries@pharmaventures.com

+44 (0) 1865 332700

Oxford, UK, 6th September 2018

PharmaVentures Ltd (“PharmaVentures”) is pleased to announce that it acted as exclusive adviser to Vital Food Processors Ltd (“Vital Foods”), an agricultural science company founded in New Zealand, on an asset purchase agreement with Mundipharma for the global rights beyond New Zealand to commercialise Zyactinase™ – a clinically-proven gastrointestinal consumer health product. Zyactinase™is the basis of market leading, natural, plant-based consumer health products for the promotion of digestive health. Zyactinase™ is a freeze-dried extract of Kiwifruit (Actinidia deliciosa) that has been developed as a constipation relief product as well as for long-term gut health. It contains a protease complex, fiber, pectin and fructo-oligosaccharides that stimulates increased bowel movements. Under the agreement, Mundipharma will initially focus on the commercialising of Zyactinase™ to establish a foothold in the US and Canada markets, while continuing to supply existing partners. It will then look to expand its marketing and distribution footprint globally. This agreement will also enable the extension of the company’s Senokot®product range in the US, which is also an all natural, clinically proven digestive health supplement for the treatment of constipation. (see http://www.prnewswire.co.uk/news-releases/mundipharma-closes-acquisition…) Adrian Dawkes, Managing Director, who led the deal at PharmaVentures, commented; “The consumer health space has seen significant deal activity recently and, not surprisingly, there was a lot of interest in Vital Foods’ assets. We are delighted to have been able to secure this deal with Mundipharma who are ideally placed to maximise the potential of Zyactinase”. Fintan Walton, Founder and Chief Executive of PharmaVentures said; “We are particularly pleased to have brought PharmaVentures’ broad experience and skills to bear in another cross-border deal where the pairing of high-quality assets from Vital Foods with an ideal acquirer in Mundipharma has resulted in an excellent outcome for all”.

PharmaVentures advises SalvaRx Group plc on the acquisition of SalvaRx Ltd by Portage Biotech Inc.

Acquisition of SalvaRx Ltd. by Portage Biotech Inc.

PharmaVentures advises SalvaRx Group plc on the acquisition of SalvaRx Ltd by Portage Biotech Inc.

For press enquiries, please contact:

Lisa Holloway

Senior Marketing Manager

PharmaVentures Ltd

enquiries@pharmaventures.com

+44 (0) 1865 332700

Oxford, UK, 20th August 2018

PharmaVentures Ltd. (“PharmaVentures”) is pleased to announce that it acted as an independent adviser to SalvaRx Group plc (SALV:LSE) (“SalvaRx”) and Portage Biotech, Inc (“Portage”), on the acquisition of its subsidiary SalvaRx Ltd by Portage. Subject to regulatory and shareholder consent, Portage will acquire 100% of SalvaRx Limited for an aggregate consideration of US$71.7 Million.

SalvaRx is a related party of Portage, the transaction is subject to the requirements of Alberta Securities Commission’s Multilateral Instrument 61-101 Protection of Minority Shareholders in Special Transactions (“MI 61-101”). As a consequence, the Transaction requires minority shareholder approval.

Although the transaction is exempt from the formal valuation requirements of MI 61-101 pursuant to Section 5.5(a) PharmaVentures was commissioned by SalvaRx and Portage to perform an independent valuation (the “Valuation”) of SalvaRx Limited. The Valuation, dated July 23, 2018, provided the parties with, amongst other things, a discussion of various methodologies to value SalvaRx Limited as well as a range of possible values.

For more information see the Portage Biotech press release.

Adrian Dawkes, Managing Director, PharmaVentures, commented; “We have worked previously with SalvaRx and were pleased to provide our extensive valuation capabilities and market knowledge to assist in this transaction”.

Fintan Walton, Founder and Chief Executive of PharmaVentures said; “PharmaVentures is trusted by long established pharmaceutical companies, governments as well as innovative biotechs like SalvaRx to provide high quality, robust and comprehensively researched valuations to support their key strategic transactions. We are pleased to have assisted SalvaRx in their endeavors”.

PharmaVentures Capital Limited advises Biosceptre International Limited, a clinical stage oncology company, on its Series A private placement by Tuspark S&T

Series A Fundraising

PharmaVentures Capital Limited advises Biosceptre International Limited, a clinical stage oncology company, on its Series A private placement by Tuspark S&T.

For press enquiries, please contact:

Lisa Holloway

Senior Marketing Manager

PharmaVentures Ltd

enquiries@pharmaventures.com

+44 (0) 1865 332700

Oxford, UK, December 15th 2017

PharmaVentures Capital Limited is pleased to announce that it acted as adviser to Biosceptre International Limited (“Biosceptre”) for the successful Series A private placement from the Chinese conglomerate Tuspark Science & Technology Service Group (Tuspark) through its investment vehicle, Bluesky Partnership II L.P. As Tuspark’s first major overseas investment into biotech, this represents a strong belief in the Biosceptre team and the potential transformative effects their therapies may bring to cancer patients.

Biosceptre’s therapies are focused upon a novel cancer target, nfP2X7, that is completely absent in healthy tissue, but present on tumour tissue in the majority of cancers, including lung, breast, colorectal and prostate. For more information on Biosceptre’s therapies see http://www.biosceptre.com/pipeline/.

This first institutional raise will allow Biosceptre to advance its three oncology clinical assets which are BIL010t, a polyclonal antibody ointment for the topical treatment of non-melanoma skin cancers, BIL06v, a peptide protein conjugate and BIL03s, fully human domain monoclonal, both for systemic uses targeting solid and blood cancers. Clinical trials are being planned in Australia, UK and EU.

Fintan Walton, Chairman and Chief Executive of PharmaVentures, said: “This investment by the Chinese company Tuspark S&T in Biosceptre represents a significant landmark for both the UK Biotechnology sector and PharmaVentures Capital Limited.”

Adrian Dawkes, Managing Director at PharmaVentures, added; “As a long-standing client, PharmaVentures is pleased to have advised Biosceptre on this transaction. We are delighted to have been able to leverage our relationships in China to secure this investment for the company.”

For the past 25 years, PharmaVentures has acted as an advisor to over 700 global pharmaceutical and biotechnology clients in transactions; many covering licensing, mergers, acquisitions, divestments and joint venture activities for companies.

About Biosceptre International

Biosceptre is a Cambridge, UK headquartered biotechnology company focused on developing next generation cancer treatments targeting nfP2X7, an oncology target with exquisite specificity.

Sir Gregory Winter, Founder of Domantis and Cambridge Antibody Technologies, is the Acting Chairman of the Biosceptre Board of Directors and he also chairs the company’s Science Advisory Board.

Biosceptre’s clinical programs include systemic antibody-based therapeutics and vaccines, intended to treat a significant range of cancer types. With one successful Phase I trial completed, Biosceptre will be progressing a number of clinical trials across a range of cancer indications. These trials will seek to further advance the establishment of nfP2X7 as a new and important target for the successful treatment of a range of human cancers.

About Tus-Holdings

Tus-Holdings is a large integrated enterprise established in reliance on Tsinghua University. It takes full responsibility for developing, constructing, operating and managing the Tsinghua University Science Park, and is one of the first National Demonstration Enterprises in modern service industry. It is the controlling shareholder of over 500 listed & non-listed enterprises, and the total assets under its management have exceeded GBP 15 billion. Tus-S&T Service Group is the equity investment platform of Tus-Holdings, who directly lead this cooperation.

This Press release is issued by PharmaVentures Capital Limited, which is authorised and regulated by the Financial Conduct Authority (FCA) and is for information purposes only. This communication does not constitute an offer or solicitation to purchase or engage in any investment products, securities or services and should not be deemed as such.

PharmaVentures advises IDT Australia on the divestment of CMAX clinical trial business to the Japanese company I’rom Group Co. Ltd.

Divestment of Clinical Trial Business CMAX to I’ROM GROUP

PharmaVentures advises IDT Australia on the divestment of CMAX clinical trial business to the Japanese company I’rom Group Co. Ltd.

For press enquiries, please contact:

Lisa Holloway

Senior Marketing Manager

PharmaVentures Ltd

enquiries@pharmaventures.com

+44 (0) 1865 332700

OXFORD, UK, October 28th, 2016

PharmaVentures is pleased to announce that it acted as adviser to IDT Australia Limited for the successful divestment of CMAX, a dedicated clinical trials business, to the Japanese healthcare company I’rom Group Co. Ltd. for a minimum AUD 14,000,000.

The acquisition is subject to the satisfaction of certain conditions precedent, and as part of the agreed upon structure of the deal, IDT will establish and integrate the CMAX business within a new company (henceforth referred to as NewCo). I’rom Group will initially acquire 61% of the shares of NewCo; and I’rom Group and IDT will jointly manage NewCo through their 61% and 39% respective share holdings. This will allow I’rom Group to integrate the CMAX business and to learn from IDT’s experience in managing CMAX, paving the way for I’rom Group to acquire the remaining shares of NewCo over the next twelve months.

IDT will receive an initial cash payment of AUD 10,000,000 in consideration for 61% of the CMAX business. A second payment for the remaining 31% of the CMAX business will be a minimum of AUD 4,000,000 (payable at I’rom Group’s election in cash or a combination of cash and forgiveness of IDT shares). The second consideration payment may increase subject to an earn-out provision and a third payment on achieving a specific business milestone.

Stephen Waterman, Managing Director, PharmaVentures said; “We are delighted to have used our expertise in the CRO sector to assist IDT in its strategic move into the specialty generics space.”

Fintan Walton, Chairman and Chief Executive of PharmaVentures said: “This deal both establishes PharmaVentures as a player in the CRO M&A space as well as continuing to demonstrate its expertise in cross-border transactions in the Asia-Pacific region.”

For the past 24 years, PharmaVentures has acted as an advisor to over 700 global pharmaceutical and biotechnology clients in transactions; covering licensing, mergers, acquisitions, divestments and joint venture activities for companies.