Issue 35

Termsheet 35

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How to survive economic ‘Head Winds’!

by Dr Fintan Walton, CEO, PharmaVentures.

The world economy is going through some tough times, again. This time the causes are well known, including China’s economically damaging zero-COVID strategy, post-COVID recovery challenges elsewhere and the impact of the unwelcome Russian invasion of Ukraine. As stocks crash and inflation rises, all global corporations are taking stock and reassessing their strategies.

In our own biotech sector, the global IPO market has effectively dried up and listed biotech stocks have dropped by 70% in value from their peak. In the UK, the Biotechnology Industry Association’s half year financial report shows that VC funding and follow-on financing is down by 50% for the first half of this year, compared to the first half of last year (2021). Clearly all this will have an impact on our industry over the next few years.

Despite the apparent gloom, the BIO Conference in the US was buzzing just a few weeks ago. The partnering activity was in full swing with thousands of meetings taking place over the four days. We at PharmaVentures attended over 150 partnering meetings – the highest number ever.

In some ways this activity is not surprising, our biopharmaceutical sector is still one of most robust largely due to the need by pharmaceutical companies to build their future patented product portfolios with novel therapies. Pharmaceutical companies cannot simply weaken their long-term strategy and, therefore, still need to compete against the competition to acquire the most promising future therapeutic candidates. Luckily, biotech companies have been well funded over the past few years and still hold a reasonable amount of cash. However, over the next year as those funds drop and valuations decline, new strategies and tactics will be required if these companies and their assets are to survive.

For 30 years, we have been advising companies through several economic cycles on robust arguments for the valuation of their assets and helping them to deploy alternative funding strategies.

To access our expertise, please contact us.

Watch: How Small/Mid-Size Firms are Shaping the Healthcare M&A Market

PharmaVentures partnered with Informa to deliver a live panel discussion in the form of a webinar.

Chaired by Dr Fintan Walton, CEO and Founder of PharmaVentures, the webinar took the form of a panel discussion with:

  • Jonathan Seaton, Head of Corporate Business Development, Bio-Rad
  • Dr Paul MacLeman, Professional Company Director
  • Dr Adrian Dawkes, Managing Director, PharmaVentures
  • Dr Jansen Jacob, Vice President, PharmaVentures

What does this webinar address?

Whilst the mega deals make the headlines, it is the smaller companies who are shaping the M&A landscape with their interesting and innovative deals. They have the drive and efficiencies that allow them to do deals more quickly.

In this webinar, the panel brought its unique insight into the issues, challenges, and benefits of doing M&A deals amongst small to mid-sized Diagnostics, MedTech, CDMO & CRO companies.
Watch to learn the answers to the following

  • Why are strategic thinking and preparation key to success?
  • How do you avoid failure in doing M&A?
  • What are the key drivers for companies taking the M&A route?
  • What are key lessons from selling and buying businesses?
  • What negotiation tactics work?
  • How important is the asset vs the people in acquiring a business?

How Small/Mid-Size Firms are Shaping the Healthcare M&A Market

How Small/Mid-Size Firms are Shaping the Healthcare M&A Market

Download Request

PharmaVentures partnered with Informa to deliver a live panel discussion . It is now available to watch on demand.

Chaired by Dr Fintan Walton, CEO and Founder of PharmaVentures, the webinar took the form of a panel discussion with:

  • Jonathan Seaton, Head of Corporate Business Development, Bio-Rad
  • Dr Paul MacLeman, Professional Company Director
  • Dr Adrian Dawkes, Managing Director, PharmaVentures
  • Dr Jansen Jacob, Vice President, PharmaVentures

What does this webinar address?

Whilst the mega deals make the headlines, it is the smaller companies who are shaping the M&A landscape with their interesting and innovative deals. They have the drive and efficiencies that allow them to do deals more quickly.

In this webinar, the panel brought its unique insight into the issues, challenges, and benefits of doing M&A deals amongst small to mid-sized Diagnostics, MedTech, CDMO & CRO companies.


Watch to learn the answers to the following

  • Why are strategic thinking and preparation key to success?
  • How do you avoid failure in doing M&A?
  • What are the key drivers for companies taking the M&A route?
  • What are key lessons from selling and buying businesses?
  • What negotiation tactics work?
  • How important is the asset vs the people in acquiring a business?

PharmaVentures advises Lausanne Hospital (CHUV) and EPFL on their collaboration and founding of Aerium Therapeutics to develop their highly potent SARS-CoV-2 antibodies

London, UK, 24 March, 2022

PharmaVentures is pleased to announce that it acted as transaction advisor to Lausanne University Hospital (CHUV) and EPFL in Switzerland on their commercial terms related to the collaboration and licensing of their highly potent SARS-CoV-2 monoclonal antibodies to the newly founded biopharmaceutical company Aerium Therapeutics, based in Boston, MA, USA and Lausanne, Switzerland.

Aerium Therapeutics is focused on discovering and developing novel monoclonal antibodies (mAbs) and antiviral treatments against SARS-CoV-2. Its initial efforts are focused on two monoclonal antibodies that, in preclinical testing, have shown potent neutralisation of important COVID-19 Variants of Concern (VOCs), including Delta, Omicron and the recent Omicron subvariants BA.1, BA.1.1, BA.2, and is thus markedly more potent than all authorised or clinically advanced anti-SARS-CoV-2 mAbs. 

The company has recently emerged with substantial Series A financial backing by the founding investor Omega Funds with the participation of F-Prime Capital. Aerium was seeded and incubated by Omega Funds in 2021 and started in collaboration with its two scientific founders, Dr. Giuseppe Pantaleo (CHUV) and Dr. Didier Trono (EPFL) in Switzerland. Both scientists are applying their substantial expertise and research capabilities to discover new mAbs against SARS-CoV-2.

This follows the recent announcement that this novel antibody is one of the most powerful identified so far against all SARS-CoV-2 variants of concern. In addition to its antiviral properties, the antibody has been designed to provide protection to those patients most vulnerable.

Fintan Walton, Founder and CEO of PharmaVentures, said “We are delighted to have advised CHUV and EPFL on their commercial terms for this break-through research that has significant potential to protect those who are left as most vulnerable to COVID-19.”

Dr. Giuseppe Pantaleo, Professor of Medicine at the CHUV, Head of Immunology and Allergy Division said “Our collaboration with Aerium Therapeutics will be key in delivering these antibodies to the clinical stage, where they have the potential to play an important role in the control and the prevention of COVID-19, particularly in all those who are not protected by vaccination.”

– Ends –

For further information, please contact:

Lisa Holloway
Senior Marketing Manager
Phone: +44 (0) 1865 332700
lisa@pharmaventures.com

Distributed by PR Newswire (Cision)

About PharmaVentures

PharmaVentures is a premier transaction advisory firm and a leading international company in partnering, M&A deals and strategic alliances. For 30 years, PharmaVentures has acted as advisor on over 900 deal related projects covering licensing, mergers, acquisitions, divestments, and joint venture activities for companies world-wide.

PharmaVentures’ deep bank of specialist experience, deal analytics and network of contacts among innovators and large pharma makes it uniquely placed to support business in all aspects of deal making and strategic planning. PharmaVentures is well known for its deep insight into deal structures and its success for generating partnering interest.

PharmaVentures’ services include:

  • M&A (divestments, mergers, acquisitions, and strategic transactions)
  • Licensing (in and out licensing)
  • Fundraising Support
  • Strategy (commercialisation, deal strategy, due diligence, market entry)
  • Valuation and Positioning (licensing, M&A, and fundraising)

NOTE: This Press release is issued by PharmaVentures Limited, whose wholly owned subsidiary PharmaVentures Capital Limited is authorised and regulated by the Financial Conduct Authority (741356). This communication is for information purposes only and does not constitute an offer or solicitation to purchase or engage in any investment products, securities or services and should not be deemed as such.

For more details, visit https://www.pharmaventures.com

About CHUV

Lausanne University Hospital is one of the five university hospitals in Switzerland, with Geneva, Bern, Basel and Zurich. With its 16 clinical and medico-technical departments and their numerous services, the CHUV is renowned for its academic achievements in health care, research, and teaching.

The CHUV is also a well-known center of medical education and research thanks to its collaboration with the Faculty of Biology and Medicine of the University of Lausanne and the Swiss Federal Institute of Technology in Lausanne (EPFL). Together, these institutions form a vast campus in the Lake Geneva region.

About EPFL

EPFL (www.epfl.ch), one of the two Swiss Federal Institutes of Technology, based in Lausanne, is Europe’s most cosmopolitan technical university with students, professors and staff from over 120 nations. A dynamic environment, open to Switzerland and the world, EPFL is centered on its three missions: teaching, research and technology transfer. EPFL works together with an extensive network of partners including other universities and institutes of technology, developing and emerging countries, secondary schools and colleges, industry and economy, political circles and the general public, to bring about real impact for society.